ReeCure

Diabetes

For the longest time in India, diabetes is known to be a disease that has been spoken under hushed whispers. The treatment therefore is one that seeks the larger interest of people. A chronic, not to mention lifelong disease; Diabetes is marked by high levels of sugar in the blood.

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Insulin, a hormone produced by the pancreas helps in the control of blood sugar. While Diabetes can be caused by too little insulin, resistance to insulin or both, its treatment becomes mandatory for patients as a large part of the Indian population is gradually being detected with high blood sugar.

Primarily, diabetes occurs because of the following reasons:
  • Pancreas don’t make enough insulin
  • Muscle, fat and liver cells do not respond to insulin as it normally should
  • All of the above

Stem Cell Facts Diabetes

The most promising treatment of diabetes involves replacement of the beta cells of the pancreas by stem cells derived from humans and cultured to differentiate into insulin positive cells.

Specifically, there are three types of diabetes:
  • Type 1 diabetes is usually diagnosed during childhood. Many patients are diagnosed when they are older than 20 years of age. In this disease, the body makes little or no insulin. For treating diabetes of this kind, daily injections of insulin are required. The exact cause however is unknown. Genetics, viruses and autoimmune problems may play a role.
  • Type 2 diabetes is far more common than type 1 and most diabetics suffer from this type. . Usually occurring during adulthood, there are young people in India today that are increasingly being diagnosed with this disease. As the pancreas don’t make enough insulin to keep blood glucose levels normal, the body does not respond well to insulin. Many people with type 2 diabetes don’t even know they are suffering from it. Though this is a serious condition, Type 2 diabetes has become far more common due to increasing obesity and failure to exercise. Treating such a condition thus becomes necessary.
  • Gestational diabetes is high blood glucose that develops at any time during pregnancy in a woman who does not have diabetes. Women who have gestational diabetes are at high risk of type 2 diabetes and cardiovascular disease later in life.
There are many risk factors for type 2 diabetes, including:
  • Age over 45 years
  • A parent, brother or sister with diabetes
  • Gestational diabetes or delivering a baby weighing more than 9 pounds
  • Heart disease
  • High blood cholesterol level
  • Obesity
  • Not getting enough exercise
  • Polycystic ovary disease (in women)
  • Previous impaired glucose tolerance
  • Some ethnic groups (particularly African Americans, Native Americans, Asians, Pacific Islanders and Hispanic Americans)

Symptoms

Symptoms of type 1 diabetes:
  • Fatigue
  • Increased thirst
  • Increased urination
  • Nausea
  • Vomiting
  • Weight loss in spite of increased appetite

Patients with type 1 diabetes usually develop symptoms over a short period of time. The condition is often diagnosed in an emergency setting.

Symptoms of type 2 diabetes:

High blood levels of glucose can cause several problem including:

  • Blurred vision
  • Fatigue
  • Increased appetite
  • Increased thirst
  • Increased urination

However, because type 2 diabetes progresses slowly, some people with high blood sugar experience no symptoms at all.

Causes & Symptoms

Diabetes is a chronic (lifelong) disease marked by high levels of sugar in the blood.

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Insulin is a hormone produced by the pancreas to control blood sugar. Diabetes can be caused by too little insulin, resistance to insulin or both.

People with diabetes have high blood sugar. This is because:
  • Their pancreas does not make enough insulin
  • Their muscle, fat and liver cells do not respond to insulin normally
  • Both of the above

Stem Cell Facts Diabetes

The most promising treatment of diabetes involves replacement of the beta cells of the pancreas by stem cells derived from humans and cultured to differentiate into insulin positive cells.

There are three major types of diabetes:
  • Type 1 diabetes is usually diagnosed in childhood. Many patients are diagnosed when they are older than age 20. In this disease, the body makes little or no insulin. Daily injections of insulin are needed. The exact cause is unknown. Genetics, viruses and autoimmune problems may play a role.
  • Type 2 diabetes is far more common than type 1 and most diabetics have it. It makes up most of diabetes cases. It usually occurs in adulthood, but young people are increasingly being diagnosed with this disease. The pancreas does not make enough insulin to keep blood glucose levels normal, often because the body does not respond well to insulin. Many people with type 2 diabetes do not know they have it, although it is a serious condition. Type 2 diabetes is becoming more common due to increasing obesity and failure to exercise.
  • Gestational diabetes is high blood glucose that develops at any time during pregnancy in a woman who does not have diabetes. Women who have gestational diabetes are at high risk of type 2 diabetes and cardiovascular disease later in life.
There are many risk factors for type 2 diabetes, including:
  • Age over 45 years
  • A parent, brother or sister with diabetes
  • Gestational diabetes or delivering a baby weighing more than 9 pounds
  • Heart disease
  • High blood cholesterol level
  • Obesity
  • Not getting enough exercise
  • Polycystic ovary disease (in women)
  • Previous impaired glucose tolerance
  • Some ethnic groups (particularly African Americans, Native Americans, Asians, Pacific Islanders and Hispanic Americans)

Symptoms

Symptoms of type 1 diabetes:
  • Fatigue
  • Increased thirst
  • Increased urination
  • Nausea
  • Vomiting
  • Weight loss in spite of increased appetite

Patients with type 1 diabetes usually develop symptoms over a short period of time. The condition is often diagnosed in an emergency setting.

Symptoms of type 2 diabetes:

High blood levels of glucose can cause several problem including:

  • Blurred vision
  • Fatigue
  • Increased appetite
  • Increased thirst
  • Increased urination

However, because type 2 diabetes progresses slowly, some people with high blood sugar experience no symptoms at all.

Medical Tests

A urine analysis may be used to look for glucose and ketones from the breakdown of fat. However, a urine test alone does not diagnose diabetes.

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The following blood tests are used to diagnose diabetes:
  • Fasting blood glucose level - diabetes is diagnosed if the glucose levels are higher than 126 mg/dL on two occasions. Levels between 100 and 126 mg/dL are referred to as impaired fasting glucose or pre-diabetes. These levels are considered to be risk factors for type 2 diabetes and its complications.
  • Oral glucose tolerance test - diabetes is diagnosed if glucose level is higher than 200 mg/dL after 2 hours. (This test is used more for type 2 diabetes.)
  • Random (non-fasting) blood glucose level - diabetes is suspected if the glucose level is higher than 200 mg/dL and accompanied by the classic diabetes symptoms of increased thirst, urination and fatigue. (This test must be confirmed with a fasting blood glucose test.)

Stem Cell Facts Diabetes

The total costs of treating diabetes for example is approaching $100 billion in the United States alone.

Persons with diabetes need to have their hemoglobin A1c (HbA1c) level checked every 3 - 6 months. The HbA1c is a measure of average blood glucose during the previous 2 - 3 months. It is a very helpful way to determine how well treatment is working.

Conventional Treatment

The immediate goals are to treat diabetic ketoacidosis and high blood glucose levels. As type 1 diabetes can start suddenly and have severe symptoms, people who are newly diagnosed may need to go to the hospital.

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The long-term goals of treatment are to:
  • Prolong life
  • Reduce symptoms
  • Prevent diabetes-related complications such as blindness, heart disease, kidney failure and amputation of limbs

Stem Cell Facts

Research shows that cord blood and embryonic stem cells could be used to revitalize a damaged immune system, for treating such immune disorders as Type 1 Diabetes, Rheumatoid Arthritis and other hereditary diseases.

These goals are accomplished through:
  • Blood pressure and cholesterol control
  • Careful self testing of blood glucose levels
  • Education
  • Exercise
  • Foot care
  • Meal planning and weight control
  • Medication or insulin use

There is no cure for diabetes. Treatment involves medicines, diet and exercise to control blood sugar and prevent symptoms.

Stem Cell Therapy

Numerous clinical trials are going on all over the world, including India using stem cells from various sources.

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We, at ReeCure offer you therapy using stem cells using our proprietary technology.

These stem cells could be of various types viz. Hematopoietic (CD 34+), Mesenchymal stem cells (MSCs) that are processed and isolated using Good Manufacturing (GMP) and Good Lab Practices (GLP) and in accordance with AABB standards.

After years of extensive research and systematic compilation and collation of relevant data (through its research division), ReeLabs is now supremely confident of not only reversing the disease process of the affected patient but also improving the quality of life manifold. Stem cells produced by ReeLabs are completely safe, non-toxic, easy to administer and totally devoid of side effects with an excellent probability of homing and engraftment with parent cell, tissue or organ. The eminent panel of scientists and researchers at ReeLabs work exhaustively to design accurate treatment protocols that have yielded excellent results in most cases.

These stem cells are procured from various sources including bone marrow, cord blood fat etc. as per the requirement of the patient

The application of stem cells in diabetics stems from the numerous trials that have pointed to formation of new islets of langerhan’s in pancreas that in turn produce more insulin and hence bring down blood sugar. This works well in Type 1 Diabetes.

In Type 2 Diabetes the hypothesis is that there is decreased resistance to insulin by the body to the newly formed islets of Langerhan’s after stem cell infusion.

Aim

The long-term goals of treatment are to:
  • Prolong life
  • Reduce symptoms
  • Prevent diabetes-related complications such as blindness, heart disease, kidney failure and amputation of limbs

Blood Glucose levels to be brought under control by oral hypoglycemics.

Criteria for selection

  • Patients with uncontrolled Blood Glucose levels.
  • Type 1 Diabetes / Type 2 Diabetes.
  • Patients with complications due to Diabetes
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