Hyaluronic acid
It is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints. It is a constituent of synovial fluid that lubricates the joints in the human body. The acid is a thick gel that not only lubricates the joints, but also protects them.
It is anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
Structure:
It is Nonsulfated glycosaminoglycans
Other name:
Hyaluronan or Hyaluronate
Source:
It is extracted from rooster combs or made by bacteria in the laboratory.
Dosage:
200 mg daily capsule dosage.No DRI established.
Mechanism of Action:
Healthy cartilage has high levels of Hyaluronic Acid which has anti-inflammatory properties. This acid also contains hyaluronate and niacinamide, which reduces swelling.
Furthermore, healthy levels of HA encourage the growth and activity of cells which are responsible for cartilage production and maintenance. When HA production decreases in the human body, people end up with conditions like arthritis.
Side Effects:
Anyone allergic to chicken or eggs should not take HA. Since the body produces Hyaluronic acid naturally, it is safe to take HA supplements.
Role:
- Hyaluronan used to treat osteoarthritis. It can be taken by mouth or injected into the affected joint by a healthcare professional.
- Injections into the knee joint, and believed to supplement the viscosity of the joint fluid, thereby :
- lubricating the joint.
- cushioning the joint.
- producing an analgesic effect.
- It has also been suggested that hyaluronan has positive biochemical effects on cartilage cells.
- Used during certain eye surgeries including cataract removal, corneal transplantation, and repair of a detached retina and other eye injuries. It is injected into the eye during the procedure to help replace natural fluids.
- Hyaluronic acid is also used as lip filler in plastic surgery.
